People
Title:Associate Professor
Subject:Microbial Resources and Biopharmaceutical
Phone:
Email:panhq@iae.ac.cn
Address:Institute of Applied Ecology, Chinese Academy of Sciences No. 72 Wenhua Road, Shenyang, Liaoning, 110016 China
Resume:

PROFESSIONAL EXPERIENCE
2015.12- present, Associate professor
Institute of Applied Ecology, Chinese Academy of Sciences
2009.07- 2015.11, Assistant professor
Institute of Applied Ecology, Chinese Academy of Sciences
2007.07- 2009.07, Research assistant
Institute of Applied Ecology, Chinese Academy of Sciences

EDUCATION

2010.09-2013.12, Ph.D. (natural product chemistry)

Shenyang Pharmaceutical University, Liaoning, China

2004.09-2007.06, M.S. (microbiology and immunology)

Gansu Agricultural University, Gansu, China

2000.09-2004.06, B.S. (veterinary medicine)

Gansu Agricultural University, Gansu, China

  • My research interests focus on using an interdisciplinary approach to study special econiche microbes and their bioactive molecules as well as drug development (especially biopesticides). There are four main aspects: 1) Microbial diversity and new microbial resources, 2) Genome mining for novel antibiotic discovery, 3) Natural product biosynthesis and metabolic engineering, 4) Biopesticide discovery and development.

  • SELECTED JOURNAL PUBLICATIONS (* Corresponding Author)

    1.         Pan H.-Q., Li Q.-L., Hu J.-C.* The complete genome sequence of Bacillus velezensis 9912D reveals its biocontrol mechanism as a novel commercial biological fungicide agent. J. Biotechnol. 2017, 247: 25-28.

    2.         Tian K.-T., Xu F.-X., Gao X., Han T., J. Li, Pan H.-Q.*, Zang L.-H., Li D.-H.*, Li Z.-L., Uchita T., Gao M., Hua H.-M.* Nitric oxide-releasing derivatives of brefeldin A as potent and highly selective anticancer agents. Eur. J. Med. Chem. 2017,136:131-143.

    3.         Pan H.-Q., Zhang D.-F., Li L., Jiang Z., Cheng J., Zhang Y.-G., Wang H.-F., Hu J.-C.*, Li W.-J.*  Nocardiopsis oceani sp. nov. and Nocardiopsis nanhaiensis sp. nov., two novel actinomycete isolated from marine sediment of South China Sea. Int. J. Syst. Evol. Microbiol. 2015, 65: 3384-3391.

    4.         Pan H.-Q.*, Hu J.-C.* Draft genome sequence of the novel strain Pseudomonas sp. 10B238 with potential ability to produce antibiotics from deep-sea sediment. Mar. Genom. 2015, 23: 55-57.

    5.         Pan, H.-Q., Cheng, J., Zhang, D.-F., Yu, S.-Y., Khieu, T.-N., Son, C. K., Jiang, Z., Hu, J.-C.*, Li, W.-J.* Streptomyces bohaiensis sp. nov., a novel actinomycete isolated from Scomberomorus niphonius in the Bohai Sea. J. Antibiot. 2015, 68 (4): 246-252.

    6.         Pan H.-Q., Yu S.-Y.,Song C.-F., Wang N., Hua H.-M.*, Hu J.-C.*, Wang S.-J. Identification and characterization of the antifungal substances of a novel Streptomyces cavourensis NA4. J. Microbiol. Biotechnol. 2015, 25 (3): 353-357.

    7.         Pan, H.-Q., Zhang, S.-Y., Wang, N., Li, Z.-L., Hua, H.-M., Hu, J.-C.*, Wang, S.-J. New spirotetronate antibiotics, lobophorins H and I, from a South China Sea-derived Streptomyces sp. 12A35. Mar. Drugs. 2013, 11: 3891-3901.

    8.         Zhang, D.-F., Pan, H.-Q. (Co-first author), He, J., Zhang, X.-M., Zhang, Y.-G., Klenk, H.-P., Hu, J.-C.*, Li, W.-J. Description of Streptomonospora sediminis sp. nov. and Streptomonospora nanhaiensis sp. nov., and reclassification of Nocardiopsis arabia (Hozzein & Goodfellow, 2008) as Streptomonospora arabica comb. nov. and emended description of the genus Streptomonospora. Int. J. Syst. Evol. Microbiol. 2013, 64: 4447-4455.

    9.         Pan, H.-Q., Wang, N., Liu, L., Liu, L., Hu, J.-C., Chen, P.-Y., Wang, S.-J., Cao, R.-B.* Molecular characterization of the duck enteritis virus UL4 gene. Virologica Sinica 2009, 24: 171-178.

    10.      Pan, H.-Q., Cao, R.-B.*, Liu, L., Niu, M.-F., Zhou, B., Chen, P.-Y., Hu, J.-C. Molecular cloning and sequence analysis of the duck enteritis virus UL5 gene. Virus research 2008, 136: 152-156.

    11.      Pan H.-Q., Cao R.-B., Chen P.-Y., Liu L., Wang S.-J., Pan G.-Y., Hu J.-C.* Application of several PCR methods in cloning unknown genes of duck enteritis virus. Microbiology 2009, 36: 1842-1848. (In chinese)

    12.      Pan H.-Q.,Zhang M., Liu L., Wang N., Hu J.-C.*, Dou D.-Q., Wang S.-J. Isolation and identification of the Fusarium solani of virulence in the Arctium lappa L. rhizosphere. Biotechnology 2009, 19: 46-59. (In chinese)

    13.      Pan H.-Q., Cao R.-B.*, Liu L.,Sun H.-L., Ji X.-B., Chen Y.-J., Chen P.-Y. Prokaryotic expression of N-terminal antigenic domain of duck plague virus gB protein and the establishment of putative indirect ELISA assay. Acta Microbiologica Sinica 2008, 48: 98-102. (In chinese)

    14.      Pan H.-Q., Liu L.*, Cao R.-B., Wei F.-H., Yuan L.-K., Li J., Sun H.-L., Pan G.-Y. Prokaryotic expression of N-terminal antigenic domain of duck plague virus gB protein and its immunological characteristics. Journol of Agricultural Biotechnology 2008, 16: 743-747. (In chinese)

    15.      Pan H.-Q., Cao R.-B., Wang N., Liu L., Hu J.-C.*, Chen P.-Y., Wang S.-J. Construction of TK gene-deleted DPV transfer vector containing Loxp and EGFP. Journal of Gansu Agricultural University 2008, 43:8-12. (In chinese)

    16.      Song D.-H., Pan H.-Q.*, Li Y.-S., Yang Y.-Z. Bioinformatic analysis of duck plague virus TK gene and TK protein. Journal of Anhui Agricultural Sciences 2007, 35:9935-9936. (In chinese)